ITDETECT: A METHOD TO DETECT INTERNAL TANDEM DUPLICATION OF FMS-LIKE TYROSINE KINASE (FLT3) FROM NEXT-GENERATION SEQUENCING DATA WITH HIGH SENSITIVITY AND CLINICAL APPLICATION

Abstract Internal tandem duplication (ITD) of Collections the FMS-like tyrosine kinase (FLT3) gene is associated with poor clinical outcomes in patients with acute myeloid leukemia.Although recent methods for detecting FLT3-ITD from next-generation sequencing (NGS) data have replaced traditional ITD detection approaches such as conventional PCR or

In modern power systems, characterized by converter-interfaced generation and electronic interface loads, system inertia ( $M_{ ext {sys}}$ ) is declining.While existing methods primarily focus on inertia estimation, a broader understanding of its impact on frequency response is imperative.This study proposes a comprehensive approach to quantify re

The genetic variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been emerging and circulating in different parts of the world from the beginning of the coronavirus disease (COVID-19) pandemic.Variants are divided into three classes: variant of interest, variant Bosch KUW20VHF0G 30cm Undercounter Wine Cooler – BLACK of co

Microbial inoculants are widely used in wastewater treatment, soil remediation, and biological control.Safety and compliance for active constituents are considered to be the most important measures of imported microbial inoculants.Microbial inoculants composition was commonly identified by phenotypic culture, which is time-consuming and labor inten

The medical images integration is the process of register and fuse them with the purpose of getting a higher quantity of diagnostic information.In this work an analysis for images integration obtained through the computerized axial tomography and the magnetic resonance is carried out, for Fridges which a tool in the Matlab program was developed, wh